Concept
Within a mixture of letters
(amino acids)
one can form several words
(immunogenic variants)
Déclion is a privately held biotechnology company focused on the development of declensional peptides for use as:
- Immunotherapeutic agents for treating neurodegenerative and autoimmune diseases
- Prophylactic and therapeutic vaccines for the treatment of infectious diseases and cancer
- Ligands for antibody discovery
Declension • n. [dih-klen-shuhn]
- The whole set of inflected forms of such a word, or the recital thereof in a fixed order
- A class of such words having similar sets of inflected forms
What is a declensional peptide?
Declensional peptides are mixtures of
40-80 amino acid-long peptides manufactured
in a single solid-phase peptide synthesis, incorporating more than one amino acid
at a given position.
Key Déclion Experience
- Eight years experience in GMP amino acid copolymer synthesis and batch-to-batch reproducibility
- Eight orthogonal analytical methods for batch release
- In vitro bioassays for batch release
- Proprietary pharmacokinetic assay methods